Updated Nov 4, 2026FDA and CMS public dataIndependent · free · not health advice
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Shortages

Why medicines run short, which ones are short now, and what to ask. 20 articles: 5 data story, 9 explainers, 1 how-to guide, 5 history.

Shortage data

5 articles

Notable shortages

8 articles
Explainer
Shortages6 min read

Lidocaine and bupivacaine, the local anesthetics that stay on FDA's shortage list

Lidocaine injection has been on FDA's shortage list since 2012 and bupivacaine since 2018. What the listings show, how FDA has patched supply, and why sterile numbing drugs keep running short.

2022History
Shortages6 min read

The 2022 contrast dye shortage, when one Shanghai plant slowed CT scans nationwide

A lockdown shut the main US supplier's contrast plant in April 2022. FDA listed iohexol and iodixanol in shortage, allowed an unapproved import, and hospitals cut contrast use by as much as half.

2023History
Shortages6 min read

The 2023 albuterol shortage, in the liquid hospitals use for nebulizers

FDA listed albuterol inhalation solution as in shortage in October 2022. A plant shutdown deepened it in 2023, and children's hospitals rewrote asthma protocols to use less of it.

2023History
Shortages6 min read

The 2023 cancer drug shortage, from one plant to most US cancer centers

How the shutdown of one plant left most large US cancer centers short of cisplatin and carboplatin in 2023, what surveys and studies measured, how FDA refilled supply, and why carboplatin is still listed in 2026.

2024History
Shortages5 min read

The 2024 IV fluid shortage

How hurricane damage to one North Carolina plant in September 2024 strained the US supply of IV fluids, what FDA and HHS did about it, and which fluids were still on FDA's shortage list in October 2026.

2022History
Shortages5 min read

The amoxicillin shortage of 2022 and 2023

FDA declared a shortage of liquid amoxicillin on Oct. 28, 2022, during a surge of respiratory illness in children. What FDA said caused it, what it did, how prescribing shifted and what pharmacies paid.

Explainer
Shortages5 min read

The code-cart drugs on FDA's shortage list, from atropine to dextrose

Atropine has been in shortage since at least 2012, sodium bicarbonate since 2017 and 50% dextrose since 2022. In November 2025 one maker said it would stop making a set of emergency syringes.

Explainer
Shortages6 min read

The GLP-1 shortages and what they meant for compounding

How semaglutide and tirzepatide went onto FDA's shortage list in 2022, how they came off in 2024 and 2025, and why those dates set the rules for compounding pharmacies and outsourcing facilities.

Causes & tracking

6 articles
Explainer
Shortages6 min read

FDA's essential medicines list, and what happened to it

A 2020 executive order had FDA list the medicines the US must always have. HHS later cut it to 86, Medicare now pays for stockpiles of them, and a third of today's shortages are on the original list.

Explainer
Shortages6 min read

How FDA tracks drug shortages

What counts as a shortage under federal law, how manufacturers must warn FDA under section 506C, what the CARES Act added in 2020, and what FDA's shortage database showed on Oct. 30, 2026.

Explainer
Shortages6 min read

How FDA works to prevent drug shortages, and where its powers stop

FDA says it helped prevent 330 shortages in 2025 using early warnings, fast-track reviews, extended expiration dates and temporary imports. Its own reports show what those tools can and cannot do.

Explainer
Shortages6 min read

Why antibiotics keep running short

Seven anti-infectives were on FDA's current shortage list in October 2026, one of them since 2015, and 30 more had discontinuation notices. Low prices and few makers explain much of it, federal research shows.

Explainer
Shortages6 min read

Why drug shortages happen

New US drug shortages fell from 251 in 2011 to four in 2025, yet old ones linger for years. FDA's 2019 root-cause analysis and later HHS research explain why cheap generic drugs run short and stay short.

Explainer
Shortages6 min read

Why sterile injectables dominate shortage lists

Injections made up 49 of the 69 drugs on FDA's current shortage list in October 2026, and their shortages ran longer. Sterile manufacturing, few producers and thin margins explain why, according to FDA and HHS.