Levothyroxine sodium tablets
Reason category: Potency out of spec
FDA recall number D-0052-2027
Thyroid
Levothyroxine 50 mcg tablet
Public data on levothyroxine from CMS and FDA: what pharmacies have paid for it, how many generic applications FDA has approved, and whether it appears in FDA's shortage or recall records.
$0.0401
NADAC per ea (2026-11)
approximate acquisition cost, not a retail price
-78%
change over five years
peak $0.3835 in 2015-02
20
approved generic applications (ANDAs) on record for Levothyroxine Sodium
11 with a product still marketed · first 2002
Not listed
in FDA's current shortage list
no matching FDA shortage entries
NADAC per unit, monthly
LEVOTHYROXINE 50 MCG TABLETShow as table
| Month | NADAC per unit ($) |
|---|---|
| 2013-11 | 0.22681 |
| 2014-02 | 0.24562 |
| 2014-05 | 0.24388 |
| 2014-08 | 0.34235 |
| 2014-11 | 0.37493 |
| 2015-02 | 0.38353 |
| 2015-05 | 0.37688 |
| 2015-08 | 0.36945 |
| 2015-11 | 0.35711 |
| 2016-02 | 0.36660 |
| 2016-05 | 0.35359 |
| 2016-08 | 0.33330 |
| 2016-11 | 0.33205 |
| 2017-02 | 0.32972 |
| 2017-05 | 0.33260 |
| 2017-08 | 0.32649 |
| 2017-11 | 0.32852 |
| 2018-02 | 0.33205 |
| 2018-05 | 0.31486 |
| 2018-08 | 0.30673 |
| 2018-11 | 0.29729 |
| 2019-02 | 0.29738 |
| 2019-05 | 0.29908 |
| 2019-08 | 0.28325 |
| 2019-11 | 0.27541 |
| 2020-02 | 0.27358 |
| 2020-05 | 0.25310 |
| 2020-08 | 0.24495 |
| 2020-11 | 0.24205 |
| 2021-02 | 0.22365 |
| 2021-05 | 0.21737 |
| 2021-08 | 0.20255 |
| 2021-11 | 0.18328 |
| 2022-02 | 0.14196 |
| 2022-05 | 0.14154 |
| 2022-08 | 0.11359 |
| 2022-11 | 0.11291 |
| 2023-02 | 0.09136 |
| 2023-05 | 0.07773 |
| 2023-08 | 0.09370 |
| 2023-11 | 0.06006 |
| 2024-02 | 0.06271 |
| 2024-05 | 0.05061 |
| 2024-08 | 0.04974 |
| 2024-11 | 0.05204 |
| 2025-02 | 0.05237 |
| 2025-05 | 0.05808 |
| 2025-08 | 0.05194 |
| 2025-11 | 0.05231 |
| 2026-02 | 0.04658 |
| 2026-05 | 0.04680 |
| 2026-08 | 0.04193 |
| 2026-11 | 0.04006 |
Source: CMS NADAC weekly files, generic rows, monthly median of weekly averages · data as of 2026-11. Figures can change and may contain errors in the source data. Check the original source before relying on them.
Recall records mentioning levothyroxine
openFDA enforcement records, by year reported.
| 2026 | 30 |
| 2025 | 17 |
| 2024 | 18 |
| 2023 | 18 |
| 2021 | 4 |
| 2020 | 22 |
| 2018 | 12 |
| 2017 | 1 |
| 2016 | 2 |
| 2015 | 1 |
189 records since 2012. A record is one product or lot, not one recall event. Combination products that contain levothyroxine are included.
What these numbers mean
NADAC is what retail pharmacies pay on average to buy the drug, published by CMS. It does not include rebates and is not what you pay at the counter. ANDA counts include all strengths and forms and applications whose products are now discontinued.
Most recent recall records
Levothyroxine sodium tablets
Reason category: Potency out of spec
FDA recall number D-0051-2027
Levothyroxine product
Reason category: Potency out of spec
FDA recall number D-0866-2026
Levothyroxine sodium tablets
Reason category: Potency out of spec
FDA recall number D-0783-2026
Levothyroxine sodium tablets
Reason category: Potency out of spec
FDA recall number D-0775-2026
Not health advice. GxRadar is for general information only. Nothing here is medical, pharmacy, legal or financial advice. Do not start, stop or change any medicine based on this site. Talk to your pharmacist or prescriber about your own situation.
Articles that mention levothyroxine
26 GxRadar articles cite or discuss this drug.
Price histories · Data story · 5 min
Levothyroxine and the price of a daily pill
Pharmacies paid 38.4 cents for a generic 50 mcg levothyroxine tablet in early 2015 and 4.0 cents in October 2026. The year-supply arithmetic, the FDA history behind the drug, and why NADAC is not what patients pay.
Equivalence & alternatives · Explainer · 5 min
Narrow therapeutic index drugs and the tighter test for their generics
Warfarin, levothyroxine, phenytoin and a few other drugs face a stricter generic test scaled to the brand's own variability. How it works, which drugs it covers and where state law adds rules.
Generic or brand · Explainer · 5 min
The pharmacist's role in generic substitution
What a pharmacist checks before swapping in a generic: the Orange Book code, the prescriber's instructions, state rules for narrow therapeutic index drugs, and the counseling duty set by OBRA '90.
Labels & identifiers · Explainer · 5 min
What 'USP' after a drug name means
The three letters point to a public quality standard that federal law makes binding. What a USP monograph covers, who writes and enforces it, and why the letters are the maker's claim and no seal of testing.
Price histories · Data story · 5 min
What pharmacies pay for a month of common generics
Thirty tablets of each of the 10 most-used generics we track cost pharmacies $35.70 in January 2014 and $8.80 in October 2026. That is acquisition cost, and the rest of the price sits on top of it.
How recalls work · How-to guide · 6 min
How to check if your medicine was recalled
Where FDA publishes every drug recall it monitors, how to match a notice to your own bottle by NDC and lot number, and the questions that get a pharmacist to a quick answer.