Updated Nov 4, 2026FDA and CMS public dataIndependent · free · not health advice
GxRadar
Drugs/Doxycycline hyclate 100 mg capsule
Antibiotic

Doxycycline hyclate 100 mg capsule

Public data on doxycycline from CMS and FDA: what pharmacies have paid for it, how many generic applications FDA has approved, and whether it appears in FDA's shortage or recall records.

$0.1079
NADAC per ea (2026-11)
approximate acquisition cost, not a retail price
-36%
change over five years
peak $3.3573 in 2013-11
89
approved generic applications (ANDAs) on record for Doxycycline Hyclate
50 with a product still marketed · first 1973
Not listed
in FDA's current shortage list
Doxycycline Hyclate Tablet: To Be Discontinued; Doxycycline Hyclate Tablet, Delayed Release: To Be Discontinued

NADAC per unit, monthly

DOXYCYCLINE HYCLATE 100 MG CAP
Show as table
MonthNADAC per unit ($)
2013-113.35730
2014-023.19332
2014-052.89746
2014-082.57290
2014-112.36131
2015-022.05156
2015-051.61631
2015-081.34782
2015-111.12972
2016-021.09030
2016-050.95879
2016-080.87195
2016-110.67381
2017-020.54637
2017-050.49188
2017-080.43396
2017-110.40202
2018-020.35168
2018-050.26062
2018-080.27125
2018-110.20398
2019-020.19511
2019-050.19949
2019-080.20264
2019-110.20746
2020-020.18901
2020-050.20317
2020-080.17312
2020-110.17011
2021-020.17834
2021-050.17853
2021-080.17991
2021-110.16974
2022-020.15612
2022-050.14213
2022-080.13869
2022-110.13627
2023-020.13511
2023-050.13947
2023-080.14174
2023-110.12965
2024-020.14353
2024-050.11158
2024-080.11803
2024-110.10861
2025-020.11281
2025-050.12672
2025-080.12147
2025-110.11688
2026-020.11453
2026-050.11485
2026-080.10673
2026-110.10794

Source: CMS NADAC weekly files, generic rows, monthly median of weekly averages · data as of 2026-11. Figures can change and may contain errors in the source data. Check the original source before relying on them.

Recall records mentioning doxycycline

openFDA enforcement records, by year reported.

20251
20241
20223
20206
20191
20185
20172
20162
20157
20143

31 records since 2012. A record is one product or lot, not one recall event. Combination products that contain doxycycline are included.

What these numbers mean

NADAC is what retail pharmacies pay on average to buy the drug, published by CMS. It does not include rebates and is not what you pay at the counter. ANDA counts include all strengths and forms and applications whose products are now discontinued.

Most recent recall records

Class IIOngoing
Doxycycline hyclate tablets
Reason category: Dissolution failure
FDA recall number D-0014-2026
Class IITerminated
Doxycycline capsules
Reason category: Labeling or packaging error
FDA recall number D-0178-2024
Class IITerminated
Doxycycline product
Reason category: Other
FDA recall number D-1182-2022
Class IITerminated
Doxycycline capsules
Reason category: cGMP deviations
FDA recall number D-1032-2022
Class IITerminated
Doxycycline hyclate tablets
Reason category: cGMP deviations
FDA recall number D-1054-2022

Not health advice. GxRadar is for general information only. Nothing here is medical, pharmacy, legal or financial advice. Do not start, stop or change any medicine based on this site. Talk to your pharmacist or prescriber about your own situation.

Articles that mention doxycycline

14 GxRadar articles cite or discuss this drug.

DOXYCYCLINE · NADAC
Price histories · Data story · 6 min

Doxycycline's 2013 price spike and the decade-long fall that followed

In late 2013 pharmacies paid $3.36 for one generic doxycycline capsule. By October 2026 they paid 11 cents. What federal records say about the spike, and how slowly the price came back down.

NITROFURANTOIN · NADAC
Price histories · Data story · 5 min

Nitrofurantoin and the antibiotic price story

Pharmacies paid $1.77 for a nitrofurantoin capsule in January 2014 and 28 cents in October 2026. How six oral antibiotics' prices diverged, why competition explains much of it, and where shortages fit.

2013
Market economics · History · 6 min

The generic price spikes of 2013 to 2015

Generic prices fell overall in the early 2010s, yet 315 established generics at least doubled in price. What GAO and HHS investigators found, what CMS price data show, and what Congress changed.

PRICE INDEX · 2014 = 100
Price histories · Data story · 6 min

The GxRadar generic price index

We priced a fixed basket of 43 common generics every month since January 2014. By October 2026 the index stood at 47.4, down about 53 percent. How it works, and where it can mislead.

Causes & tracking · Explainer · 6 min

Why antibiotics keep running short

Seven anti-infectives were on FDA's current shortage list in October 2026, one of them since 2015, and 30 more had discontinuation notices. Low prices and few makers explain much of it, federal research shows.

Manufacturing quality · Explainer · 6 min

Dissolution testing, the lab check behind many tablet recalls

How a dissolution test measures whether a pill releases its drug, how USP and FDA set the pass mark, and what 414 recall records citing dissolution show about which products fail.