Updated Nov 4, 2026FDA and CMS public dataIndependent · free · not health advice
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Drugs/Sertraline 50 mg tablet
Mental health

Sertraline 50 mg tablet

Public data on sertraline from CMS and FDA: what pharmacies have paid for it, how many generic applications FDA has approved, and whether it appears in FDA's shortage or recall records.

$0.0348
NADAC per ea (2026-11)
approximate acquisition cost, not a retail price
-22%
change over five years
peak $0.0682 in 2020-08
34
approved generic applications (ANDAs) on record for Sertraline Hydrochloride
21 with a product still marketed · first 2006
Not listed
in FDA's current shortage list
no matching FDA shortage entries

NADAC per unit, monthly

SERTRALINE HCL 50 MG TABLET
Show as table
MonthNADAC per unit ($)
2013-110.05058
2014-020.05552
2014-050.05456
2014-080.05427
2014-110.05479
2015-020.05186
2015-050.05260
2015-080.05800
2015-110.05573
2016-020.05228
2016-050.05698
2016-080.04997
2016-110.04888
2017-020.05211
2017-050.04747
2017-080.04706
2017-110.04774
2018-020.04733
2018-050.04495
2018-080.04382
2018-110.04294
2019-020.04684
2019-050.04093
2019-080.04444
2019-110.04612
2020-020.04262
2020-050.04286
2020-080.06817
2020-110.04920
2021-020.05474
2021-050.04863
2021-080.04881
2021-110.04459
2022-020.04157
2022-050.04452
2022-080.04358
2022-110.04188
2023-020.03919
2023-050.04450
2023-080.04589
2023-110.04057
2024-020.04184
2024-050.03586
2024-080.03551
2024-110.03440
2025-020.03488
2025-050.03656
2025-080.03606
2025-110.03671
2026-020.03753
2026-050.03453
2026-080.03456
2026-110.03484

Source: CMS NADAC weekly files, generic rows, monthly median of weekly averages · data as of 2026-11. Figures can change and may contain errors in the source data. Check the original source before relying on them.

Recall records mentioning sertraline

openFDA enforcement records, by year reported.

20251
20241
20181
20161
20151
20142

7 records since 2012. A record is one product or lot, not one recall event. Combination products that contain sertraline are included.

What these numbers mean

NADAC is what retail pharmacies pay on average to buy the drug, published by CMS. It does not include rebates and is not what you pay at the counter. ANDA counts include all strengths and forms and applications whose products are now discontinued.

Most recent recall records

Class IIOngoing
Sertraline hydrochloride tablets
Reason category: Other
FDA recall number D-0227-2026
Class IIOngoing
Sertraline hydrochloride tablets
Reason category: cGMP deviations
FDA recall number D-0205-2024
Class IITerminated
Sertraline product
Reason category: Potency out of spec
FDA recall number D-0151-2018
Class IITerminated
Sertraline product
Reason category: Failed specifications (other)
FDA recall number D-0857-2016
Class IITerminated
Sertraline product
Reason category: Sterility / contamination
FDA recall number D-891-2015

Not health advice. GxRadar is for general information only. Nothing here is medical, pharmacy, legal or financial advice. Do not start, stop or change any medicine based on this site. Talk to your pharmacist or prescriber about your own situation.

Articles that mention sertraline

15 GxRadar articles cite or discuss this drug.

PRICE INDEX · 2014 = 100
Price histories · Data story · 6 min

What pharmacies paid for six generic antidepressants, 2013 to 2026

Federal NADAC data for sertraline, escitalopram, citalopram, fluoxetine, trazodone and duloxetine show three very different price paths since 2013, and FDA approval records help explain them.

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Labels & identifiers · How-to guide · 5 min

How to look up a drug on DailyMed

DailyMed is the National Library of Medicine's free archive of drug labels as companies submit them to FDA. How to search it by name or NDC, find inactive ingredients and imprints, and tell the leaflets apart.

Labels & identifiers · Explainer · 5 min

Medication Guides and patient package inserts

What 21 CFR Part 208 requires, when a pharmacy must hand over a Medication Guide, how patient package inserts differ, and where FDA's one-page replacement proposal stands.

Labels & identifiers · Explainer · 6 min

Boxed warnings, FDA's most prominent label warning, explained

What 21 CFR 201.57 requires of a boxed warning, how many prescription labels carry one (about a third, by two counts 14 years apart), and why a generic's box matches the brand's.

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Cash price & comparison · How-to guide · 6 min

How to compare pharmacy cash prices for a generic prescription

A 2014 phone survey found one generic antibiotic priced from $5 to $229 in a single county. How to compare cash quotes by phone, and how to read them against NADAC.

The approval pathway · Explainer · 5 min

Pediatric exclusivity and the six months it adds before generics

A brand company that studies its drug in children at FDA's written request can win six more months of protection from generics. How the 1997 incentive works, what it attaches to, and what FDA's own lists show.